Meta-analysis: formulating, evaluating, combining, and reporting.
نویسنده
چکیده
Meta-analysis involves combining summary information from related but independent studies. The objectives of a meta-analysis include increasing power to detect an overall treatment effect, estimation of the degree of benefit associated with a particular study treatment, assessment of the amount of variability between studies, or identification of study characteristics associated with particularly effective treatments. This article presents a tutorial on meta-analysis intended for anyone with a mathematical statistics background. Search strategies and review methods of the literature are discussed. Emphasis is focused on analytic methods for estimation of the parameters of interest. Three modes of inference are discussed: maximum likelihood; restricted maximum likelihood, and Bayesian. Finally, software for performing inference using restricted maximum likelihood and fully Bayesian methods are demonstrated. Methods are illustrated using two examples: an evaluation of mortality from prophylactic use of lidocaine after a heart attack, and a comparison of length of hospital stay for stroke patients under two different management protocols.
منابع مشابه
Tutorial in biostatistics. Meta-analysis: formulating, evaluating, combining, and reporting by S-L. T. Normand, Statistics in Medicine, 18, 321-359 (1999)
متن کامل
ارزیابی کیفیت گزارش مطالعات مرور نظام‌مند و فراتحلیل در مجلات پرستاری و مامایی ایران
Background & Aim: In the view of the importance of evidence-based clinical practice in recent years, clinical disciplines such as nursing and midwifery have found a special need to systematic review and meta-analysis. However, systematic reviews and meta-analysises like any other studies may be poorly designed and implemented. Therefore, certain guidelines have been considered for reporting of ...
متن کاملThe attitudes of nurses towards the occurrence and reporting of nursing errors in selected hospitals of Tehran University of Medical Sciences in 2019
Introduction: Nurses have an undeniable role in preventing nursing and medical errors, and evaluating their attitude towards error reporting, as a strategic indicator, can help nursing managers in preventing errors and improving patient safety and quality of nursing care. Therefore, this study was conducted with the aim of determining the attitude of nurses towards the occurrence and reporti...
متن کاملGuidelines for meta-analyses evaluating diagnostic tests.
OBJECTIVES To introduce guidelines for the conduct, reporting, and critical appraisal of meta-analyses evaluating diagnostic tests and to apply these guidelines to recently published meta-analyses of diagnostic tests. DATA SOURCES Based on current concepts of how to assess diagnostic tests and conduct meta-analyses. They are applied to all meta-analyses evaluating diagnostic tests published i...
متن کاملA systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery
OBJECTIVE Our objective was to evaluate quality of conduct and reporting of published systematic reviews and meta-analyses in paediatric surgery. We also aimed to identify characteristics predictive of review quality. BACKGROUND Systematic reviews summarise evidence by combining sources, but are potentially prone to bias. To counter this, the Preferred Reporting Items for Systematic Reviews a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Statistics in medicine
دوره 18 3 شماره
صفحات -
تاریخ انتشار 1999